发明名称 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING VLA-4
摘要 The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to VLA-4 integrin antagonists to target cells expressing VLA-4.
申请公布号 CA2854254(A1) 申请公布日期 2013.08.01
申请号 CA20132854254 申请日期 2013.01.24
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GOODNOW, ROBERT ALAN, JR.;HAMILTON, MATTHEW MICHAEL;SIDDURI, ACHYUTHARAO
分类号 A61K47/48;A61P29/00;A61P35/00 主分类号 A61K47/48
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