| 发明名称 |
HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES |
| 摘要 |
The invention relates to compounds of Formula (1) and to processes for the preparation of intermediates used in the preparation of compositions containing and the uses of such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.
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| 申请公布号 |
US2013196952(A1) |
申请公布日期 |
2013.08.01 |
| 申请号 |
US201113695770 |
申请日期 |
2011.05.04 |
| 申请人 |
BUNNAGE MARK EDWARD;COOK ANDREW SIMON;CUI JINGRONG JEAN;DACK KEVIN NELL;DEAL JUDITH GAIL;GU DANLIN;HE MINGYING;JOHNSON PATRICK STEPHEN;JOHNSON TED WILLIAM;LE PHUONG THI QUY;PALMER CYNTHIA LOUISE;SHEN HONG;PFIZER INC. |
发明人 |
BUNNAGE MARK EDWARD;COOK ANDREW SIMON;CUI JINGRONG JEAN;DACK KEVIN NELL;DEAL JUDITH GAIL;GU DANLIN;HE MINGYING;JOHNSON PATRICK STEPHEN;JOHNSON TED WILLIAM;LE PHUONG THI QUY;PALMER CYNTHIA LOUISE;SHEN HONG |
| 分类号 |
C07D213/73;C07D241/20;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D403/14;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D451/02;C07D471/04;C07D498/04;C07F9/6558 |
主分类号 |
C07D213/73 |
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