| 摘要 |
PROBLEM TO BE SOLVED: To provide a method of producing a difluoroacetic acid ester with high selectivity in good yield while preventing generation of byproducts.SOLUTION: In a method of producing a difluoroacetic acid ester represented by general formula HCFCOOR wherein R is a lower alkyl group, 1,1,2,2-tetrafluoroethyl alkyl ether represented by general formula HCFCFOR wherein R is a lower alkyl group is brought into contact with an acid catalyst in the presence of an oxide and a lower alcohol represented by general formula ROH wherein R is a lower alkyl group. In the method, a reaction temperature is 20-60°C, and a usage amount of the acid catalyst is 0.1-0.5 mole for 1 mol of 1,1,2,2-tetrafluoroethyl alkyl ether. |
