IMPROVED NITAZOXANIDE COMPOSITION AND PREPARATION METHOD THEREOF

摘要

The invention relates to an orally administered pharmaceutical nitazoxanide composition used for the treatment of intestinal parasitic infections, in the form of granules for suspension, in which said composition contains: (a) an immediate release fraction formed by uncoated granules or non-granular powder of nitazoxanide, and (b) a pH-dependent release fraction formed by granules of nitazoxanide coated with one or more polymers having a pH-dependent solubility.