Process for producing preparation for oral administration

摘要

A process for producing or continuously producing a preparation for oral administration, the preparation comprising a first water-swellable gel-forming layer as an outermost layer, a second water-swellable gel-forming layer as another outermost layer, and a drug enclosed in an enclosing part formed by bonding peripheral parts of the first and second water-swellable gel-forming layers to each other directly or through an adhesive layer. This production process or continuous production process comprises the following steps: (a) the step of forming a first water-swellable gel-forming layer, (b) the step of forming a recessed part in a given area of the first water-swellable gel-forming layer, (c) the step of packing a drug into the recessed part formed, and (d) the step of forming a second water-swellable gel-forming layer over the packed drug directly or through an adhesive layer and bonding the layers together in a peripheral part surrounding the recessed part.