发明名称 |
A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS |
摘要 |
The claimed subject matter relates to allosteric modulation of A3 adenosine receptor (A3AR) and provides for the use of an A3 adenosine receptor modulator (A3RM), for the preparation of pharmaceutical compositions for modulating the A3AR in a subject, as well as pharmaceutical compositions including the same and therapeutic methods including administering to a subject an amount of an A3RM, the amount being effective to modulate A3AR activity. The A3RM according to claimed subject matter are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives. Also provided are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives.
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申请公布号 |
US2013197025(A1) |
申请公布日期 |
2013.08.01 |
申请号 |
US201313800560 |
申请日期 |
2013.03.13 |
申请人 |
GOEBLYOES ANIKO;BRUSSEE JOHANNES;IJZERMAN ADRIAAN P.;GAO ZHAN-GUO;JACOBSON KENNETH;UNIVERSITEIT LEIDEN;THE GOVERNMENT OF THE UNITED STATE OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND |
发明人 |
GOEBLYOES ANIKO;BRUSSEE JOHANNES;IJZERMAN ADRIAAN P.;GAO ZHAN-GUO;JACOBSON KENNETH |
分类号 |
A61K31/4745 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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地址 |
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