| 发明名称 |
BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION |
| 摘要 |
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
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| 申请公布号 |
US2013196973(A1) |
申请公布日期 |
2013.08.01 |
| 申请号 |
US201213418377 |
申请日期 |
2012.03.13 |
| 申请人 |
ABEYWARDANE ASITHA;BURKE MICHAEL J.;KIRRANE THOMAS MARTIN;NETHERTON MATTHEW RUSSELL;PADYANA ANIL KUMAR;SMITH KEENAN LANA LOUISE;TAKAHASHI HIDENORI;TURNER MICHAEL ROBERT;ZHANG QIANG;ZHANG QING;BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
ABEYWARDANE ASITHA;BURKE MICHAEL J.;KIRRANE THOMAS MARTIN;NETHERTON MATTHEW RUSSELL;PADYANA ANIL KUMAR;SMITH KEENAN LANA LOUISE;TAKAHASHI HIDENORI;TURNER MICHAEL ROBERT;ZHANG QIANG;ZHANG QING |
| 分类号 |
C07D319/20;C07D405/10;C07D405/14;C07D417/10;C07D417/14;C07D471/10;C07D487/04;C07D487/08;C07D487/10;C07D491/056 |
主分类号 |
C07D319/20 |
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