发明名称 Pyrimidine gyrase and topoisomerase IV inhibitors
摘要 The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti¬ bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
申请公布号 AU2012205415(A1) 申请公布日期 2013.08.01
申请号 AU20120205415 申请日期 2012.01.13
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 LE TIRAN, ARNAUD;GRILLOT, ANNE-LAURE;CHARIFSON, PAUL S.;BENNANI, YOUSSEF LAAFIRET;O'DOWD, HARDWIN;PEROLA, EMANUELE
分类号 C07D405/14;A61K31/506;A61P31/04;C07F9/6558 主分类号 C07D405/14
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