发明名称 |
Method for increasing the yield of an interferon alpha composition |
摘要 |
<p>The present invention provides methods for isolating adjunct isoforms of proteins and converting them to the desired protein. In preferred embodiments, the present invention contemplates the use of acid solutions or zinc solutions to cleave a chemical group from a desired protein. In further preferred embodiments, the present invention contemplates the oxidation of reduced sulfhydryl groups with cleavage of chemical groups to form a functional desired protein.</p> |
申请公布号 |
IL142546(A) |
申请公布日期 |
2013.07.31 |
申请号 |
IL20010142546 |
申请日期 |
2001.04.11 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
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分类号 |
A61K;C07K14/52;A61K38/00;C07K;C07K1/02;C07K1/16;C07K14/56 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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