Single domain - Fc fusion constructs

摘要

A simple method for generating antibody-based structures suitable for <Italic>in vivo</Italic> use. A method for the generation of antibody-based structures suitable for <Italic>in vivo</Italic> use comprising the steps of: (a) selecting an antibody single variable domain having an epitope binding specificity; and (b) attaching the single domain of step (a) to an effector group. Uses of molecules generated using the method are also described.