摘要 |
<p>Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful asβ-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors ofβ-lactamases. These compounds restore/potentiate the activities ofβ-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detectingβ-lactamases. Formula (I)</p> |
申请人 |
ALLECRA THERAPEUTICS GMBH |
发明人 |
UDAYAMPALAYAM PALANISAMY, SENTHILKUMAR;PAUL-SATYASEELA, MANEESH;NARAYANAN, SHRIDHAR;BALASUBRAMANIAN, GOPALAN;APPU, ARAVIND;MANICKAM, SENTHILNATHAN;PERIASAMY, HARIHARAN |