发明名称 INFUSION PREPARATION
摘要 An object of the present invention is to provide aninfusion preparation in which the Maillard reaction between anmino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only oneof the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition thatcan be communicably opened, wherein a first chamber contains afirst-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.0, the second-chamber infusion has apotassium concentration of 40 mEq/L or less and a relative osmotic pressure of 2.5 to 3.5, and a mixture of the first- and second-chamber infusions has a potassium concentration of 16mEq/L or more as measured upon communicably opening the partition.
申请公布号 SG190915(A1) 申请公布日期 2013.07.31
申请号 SG20130041249 申请日期 2011.11.28
申请人 OTSUKA PHARMACEUTICAL FACTORY, INC. 发明人 TANI, SEIJI;MITSUMOTO, YASUHIRO
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