Type 1 pancreatic elastase protein, a nucleic acid molecule encoding the protein, a vector, a host cell, methods of producing the protein and a pharmaceutical composition comprising the protein and the use thereof

摘要

Methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins. Described are recombinant methods for producing therapeutically useful elastase proteins, as are pharmaceutical compositions comprising said elastase proteins. Novel recombinant elastase proteins and protein preparations are also disclosed. Methods are described for treating and preventing diseases of biological conduits using pharmaceutical compositions containing the elastase proteins of the invention.