发明名称 OLIGOMER-SPECIFIC AMYLOID BETA EPITOPE AND ANTIBODIES
摘要 An isolated antibody that specifically binds to a cyclic peptide comprising the conformational epitope which has at least the amino acid sequences GSNK or SNKG, wherein the K (lysine) is solvent-exposed and wherein the antibody can specifically bind to amyloid beta is described. Methods of treating and preventing Alzheimer's disease, as well as methods to produce the antibody, are also described.
申请公布号 EP2542571(A4) 申请公布日期 2013.07.31
申请号 EP20110750124 申请日期 2011.03.03
申请人 THE UNIVERSITY OF BRITISH COLUMBIA 发明人 CASHMAN, NEIL R.
分类号 C07K14/47;A61K39/00;A61K39/395;A61P25/28;A61P37/04;C07K7/06;C07K7/64;C07K16/18;C12N15/13;G01N33/53;G01N33/68 主分类号 C07K14/47
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