发明名称 PHARMACEUTICAL COMPOSITIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIODIN-2-YL)BENZOIC ACID AND ADMINISTRATION THEREOF
摘要 A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.
申请公布号 ZA201208225(B) 申请公布日期 2013.07.31
申请号 ZA20120008225 申请日期 2012.11.01
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 VERWIJS MARINUS JACOBUS;KAUSHIK RITU ROHIT;YOUNG CHRISTOPHER RYAN;ALARGOVA ROSSITZA GUEORGUIEVA;KADIYALA IRINA NIKOLAEVNA
分类号 A61K;C07D 主分类号 A61K
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