发明名称 |
A NUCLEIC ACID HAVING AN ANTI-METABOLIC SYNDROME EFFECT |
摘要 |
<p>The problem of the present invention is to prove a medicament for decreasing body weigh, a medicament for decreasing visceral fat, a medicament for decreasing triglyceride in the liver, and a method for screening a medicament for ameliorating obesity and fatty liver. The problem is solved by a method comprising measuring an activity of a candidate material for inhibiting a sphingomyelin synthetase wherein if the candidate material has an activity for inhibiting a sphingomyelin synthetase, the candidate material is judged to have at least one function selected from the consisting of an anti-obesity drug, a drug for decreasing visceral fat, a drug for treating fatty liver and an agent for increasing adiponectin expression.</p> |
申请公布号 |
EP2619310(A2) |
申请公布日期 |
2013.07.31 |
申请号 |
EP20110784801 |
申请日期 |
2011.09.21 |
申请人 |
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;SHIONOGI & CO., LTD. |
发明人 |
MITSUTAKE, SUSUMU;ZAMA, KOTA;IGARASHI, YASUYUKI;YOSHIDA, TETSUYA;TANAKA, YOSHIKAZU;TAKEMOTO, HIROSHI |
分类号 |
C12N15/113;A61K31/712;A61K31/713 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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