发明名称 ANTIANGIOGENIC ACTIVE IMMUNOTHERAPY
摘要 Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis. These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.
申请公布号 CA2480079(C) 申请公布日期 2013.07.30
申请号 CA20032480079 申请日期 2003.04.11
申请人 CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA 发明人 BEQUET ROMERO, MONICA;ACEVEDO CASTRO, BORIS ERNESTO;GAVILONDO COWLEY, JORGE VICTOR;FERNANDEZ MOLINA, LUIS ENRIQUE;LOPEZ OCEJO, OMAR;SILVA RODRIGUEZ, RICARDO DE LA CARIDAD;MUSACHIO LASA, ALEXIS;GALBAN RODRIGUEZ, ERNESTO;VAZQUEZ BLOMQUIST, DANIA MARCIA
分类号 A61K38/18;A61K38/17;A61K39/00;A61K48/00;A61P43/00;C07K14/475;C07K14/515;C07K14/52;C07K14/71;C07K14/715;C12N15/12 主分类号 A61K38/18
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