| 发明名称 |
FUSED PENTACYCLIC POLYETHERS |
| 摘要 |
Disclosed are polycyclic polyether compounds of formula: (I) and pharmaceutical compositions comprising such compounds. Wherein R, OR1 and R2 are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.
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| 申请公布号 |
CA2539588(C) |
申请公布日期 |
2013.07.30 |
| 申请号 |
CA20042539588 |
申请日期 |
2004.09.20 |
| 申请人 |
UNIVERSITY OF NORTH CAROLINA AT WILMINGTON |
发明人 |
BADEN, DANIEL G.;ABRAHAM, WILLIAM M.;BOURDELAIS, ANDREA J.;MICHELLIZA, SOPHIE |
| 分类号 |
C07D493/22;A61K31/35;A61K31/353;A61K31/42;A61K31/7072;A61P11/00;C07D493/04;C07D493/14;C07H19/04 |
主分类号 |
C07D493/22 |
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