| 发明名称 |
TETRASUBSTITUTED PYRIDAZINES HEDGEHOG PATHWAY ANTAGONISTS |
| 摘要 |
The present invention provides novel tetrasubstituted pyridazineswherein Ris hydrogen, fluoro or cyano; and Rand Rare independently methyl or hydrogen; or a pharmaceutically acceptable salt thereof as hedgehog pathway antagonists useful in the treatment of cancer. |
| 申请公布号 |
EA018372(B1) |
申请公布日期 |
2013.07.30 |
| 申请号 |
EA20110070700 |
申请日期 |
2009.11.09 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
CLAY JULIA, MARIE;HIPSKIND PHILIP, ARTHUR;SALL DANIEL, JON;WILSON (NEE TAKAKUWA) TAKAKO;THOMPSON MICHELLE, LEE;BASTIAN JOLIE, ANNE |
| 分类号 |
C07D403/04;A61K31/501;A61P35/00 |
主分类号 |
C07D403/04 |
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