INJECTABLE POLYMER FORMULATION CONTAINING GENE COMPLEX

摘要

PURPOSE: An injectable polymer formulation including a specific gene complex is provided to have a passive urinary incontinence treatment effect with a polymer mixture matrix including micro particles in the early stage of injection, and to induce stable and continuous production/emission by including a specific gene complex capable of regenerating damaged sphincter, blood vessel and nerve near urethra. CONSTITUTION: An injectable polymer formulation includes a gene complex and a polymer mixture matrix. The gene complex is sustained-released from the polymer mixture matrix. The gene complex includes cationic polymer and plasmid DNA (pDNA) capable of producing a bioactive substance by being introduced into the cell. The bioactive substance is continuously produced and released from the introduced cell. [Reference numerals] (AA) Normal group; (BB) Control group; (CC) Comparative example 1; (DD) Example 1