发明名称 |
Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby |
摘要 |
Methods are described for measuring the amount of a methylation TPMT enzyme product in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying 6-MMP or isotopically labeled 6-MMP in a test sample utilizing mass spectrometric techniques and for using such methods to determine the activity of TPMT enzyme that is present in a sample.
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申请公布号 |
US8497471(B2) |
申请公布日期 |
2013.07.30 |
申请号 |
US201113232861 |
申请日期 |
2011.09.14 |
申请人 |
HADDON WILLIAM F.;CLARKE NIGEL J.;QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
发明人 |
HADDON WILLIAM F.;CLARKE NIGEL J. |
分类号 |
B01D59/44 |
主分类号 |
B01D59/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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