| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to immunology. What is presented is a composition containing at least two antibodies which bind different epitopes of human EGFR (ErbB-1) thereby providing a synergetic effect; what is also presented is a bi-specific molecule representing an antibody or a fragment thereof containing sequences of CDR antibodies as a part of the composition according to the invention. What is considered is the use of the composition according to the invention for preparing a drug and a pharmaceutical composition containing the composition according to the invention.EFFECT: composition according to the present invention provides a synergetic effect of anti-EGFR antibodies that can find further application in treating cancer.20 cl, 17 tbl, 21 ex, 42 dwg |
