发明名称 DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR UTERINE CANCER
摘要 FIELD: medicine.SUBSTANCE: invention provides the differential diagnostic technique for uterine cancer wherein s neutrophil suspension (NS) prepared of fresh heparin venous blood, exposed to femtosecond laser light (FSLL) in different doses; NF is examined for activities of myeloperoxidase (MPO), acid phosphatase (AP), cationic protein (CP) and activity in nitroblue tetrazolium (NBT) test. In initial uterine cancer (1a according to FIGO), CPs are more than an average cytochemical coefficient (ACC) of 1.65 in the NS after average-dose FSLL of 84.53 mJ/cm, while AC is more than ACC of 0.96 with normal CP being below ACC of 1.65, and AP is more than ACC of 0.96; in a locally advanced process (Ib-IIa according to FIGO) of uterine cancer, NBT is more than ACC of 1.45 after average-dose FSLL of 23.7 mJ/cm, and MPO is less than ACC of 2.22; in advanced uterine cancer (Ilb-IV according to FIGO), AC is less than ACC of 1.28 with FSLL of 8.5 mJ/cm, and NBT is less than ACC of 1.38 with FSLL of 71.1 mJ/cm.EFFECT: technique enables determining the stage of uterine cancer.
申请公布号 RU2488823(C1) 申请公布日期 2013.07.27
申请号 RU20120107983 申请日期 2012.03.01
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "UL'JANOVSKIJ GOSUDARSTVENNYJ UNIVERSITET" 发明人 GENING TAT'JANA PETROVNA;GENING SNEZHANNA OLEGOVNA;ABAKUMOVA TAT'JANA VLADIMIROVNA;ARSLANOVA DINARA RISHATOVNA;ANTONEEVA INNA IVANOVNA;RJABOVA LIDIJA GEORGIEVNA;SIDORENKO EKATERINA GENNAD'EVNA
分类号 G01N33/49;G01N33/53 主分类号 G01N33/49
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