发明名称 INDOLE COMPOUNDS
摘要 596024 Disclosed are indole derivatives of formula A that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole. Examples of compounds of formula A are: 1-[(4-chlorophenyl)methyl]-N-(3-fluoro-4-pyridinyl)-5-methoxy-2-methyl-alpha-oxo-1H-Indole-3-acetamide 1-[(2,4-difluorophenyl)methyl]-N-(2-methoxy-4-pyridinyl)-2,5-dimethyl-alpha-oxo-1H-Indole-3-acetamide N-(2-chloro-4-pyridinyl)-5-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-alpha-oxo-1H-Indole-3-acetamide N-(2-chloro-4-pyridinyl)-1-[(4-fluorophenyl)methyl]-5-methoxy-2-methyl-?-oxo-1H-Indole-3-acetamide
申请公布号 NZ596024(A) 申请公布日期 2013.07.26
申请号 NZ20070596024 申请日期 2007.08.07
申请人 IRONWOOD PHARMACEUTICALS, INC. 发明人 TALLEY, JOHN, JEFFREY;SPROTT, KEVIN;PEARSON, JAMES PHILIP;MILNE, TODD, G
分类号 C07D401/12 主分类号 C07D401/12
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