摘要 |
<p>An assay device for determining the concentration of multiple analytes or controls, where the device is capable of determining the presence or concentration of at least six analytes or controls includes: a fluid flow path; a liquid sample addition zone; a reagent zone downstream and in fluid communication with the sample addition zone containing one or more reagents; multiple detection zones in fluid communication with the reagent zone. The fluid flow path, which extends through the detection zones, has a length capable of having at least six detection zones linearly spaced at least a sufficient distance apart in order to discriminate each signal peak from its adjacent signal peak. The device further includes a wicking zone in fluid communication with the detection zones having a capacity to receive liquid sample flowing from the detection zone. The fluid flow path extends from the sample zone to the wicking zone, and at least a part of the fluid flow path has a substrate and projections which extend substantially vertically from the substrate. The projections have a height, cross-section and a distance between one another that defines a space between the projections capable of generating capillary flow parallel to the substrate surface.</p> |
申请人 |
ORTHO-CLINICAL DIAGNOSTICS, INC. |
发明人 |
DANIELSON, SUSAN;KANALEY, JAMES D.;DING, ZHONG;HOSIMER, PHILIP C.;HASSETT, JAMES W.;WARREN, TIMOTHY C.;HEAVNER, DAVID A. |