发明名称 MODULE-LEVEL ANALYSIS OF PERIPHERAL BLOOD LEUKOCYTE TRANSCRIPTIONAL PROFILE
摘要 PROBLEM TO BE SOLVED: To provide a method for obtaining individual gene expression levels from cells obtained from one or more patients with a disease or condition, and a method for the diagnosis and prognosis of disease from transcriptional expression.SOLUTION: An apparatus, system and method for the development and use of transcriptional modules includes: recording the expression value for each gene in a table that is divided into clusters; iteratively selecting gene expression values for one or more transcriptional modules by selecting for the module the genes from each cluster that match in every disease or condition and removing the selected genes from the analysis; repeating the process of gene expression value selection for genes that cluster in a sub-fraction of the diseases or conditions; and iteratively repeating the generation of modules.
申请公布号 JP2013143948(A) 申请公布日期 2013.07.25
申请号 JP20130042651 申请日期 2013.03.05
申请人 BAYLOR RESEARCH INST 发明人 CHAUSSABEL DAMIEN;BANCHEREAU JACQUES F
分类号 C12Q1/68;C12N15/09 主分类号 C12Q1/68
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