发明名称 |
NANOFIBER SCAFFOLDS AND METHODS FOR REPAIRING DAMAGED CARDIAC TISSUE |
摘要 |
Compositions are provided comprising a nanofiber scaffold that is seeded with one or more relevant cells and has a basketweave configuration that mimics the structure of a tissue, such as a cardiac tissue. Methods for treating damaged cardiac tissue in a subject are also provided and include applying an effective amount of the composition to damaged cardiac tissue. Methods for making nanofiber scaffold compositions are further provided and include electrospinning a biodegradable polymer onto a mandrel to create a mat of electrospun nanofibers, dividing the mat into nanofiber strips; and weaving the strips into a nanofiber scaffold having a basketweave configuration that mimics the structure of a tissue.. |
申请公布号 |
WO2013109642(A1) |
申请公布日期 |
2013.07.25 |
申请号 |
WO2013US21762 |
申请日期 |
2013.01.16 |
申请人 |
MARSHALL UNIVERSITY RESEARCH CORPORATION |
发明人 |
XIE, JINGWEI |
分类号 |
A61L27/56;A61L27/04;A61L27/14;A61L27/38 |
主分类号 |
A61L27/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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