发明名称 |
Hyaluronidase and Method of use Thereof |
摘要 |
The present invention provides a tnaluronidase. The hyaiuronidase can be produced by the strain Streptomyces aitinocidm 77. Exemplary characteristics of the hyaluronidase include specific C-terminal or other amino acid sequences, including full-length sequences, and improved physico-chemical and actix itj properties as compared to known h>alnuronidase preparatkiiis. Described are also various uses of the hyaiuronidase, including topical administration of the h>aiuronidase to improve skin penetration of a co-administered active substance.
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申请公布号 |
US2013189242(A1) |
申请公布日期 |
2013.07.25 |
申请号 |
US201213620470 |
申请日期 |
2012.09.14 |
申请人 |
UVARKINA TAMARA P.;KAHOJAN EUGENE G. |
发明人 |
UVARKINA TAMARA P.;KAHOJAN EUGENE G. |
分类号 |
C12N9/24;A61K31/167;A61K31/245;A61K38/28;A61K38/47;A61K45/06 |
主分类号 |
C12N9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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