发明名称 |
Use of Leptin for Treating Human Lipoatrophy and Method of Determining Predisposition to Said Treatment |
摘要 |
Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment. |
申请公布号 |
US2013190225(A1) |
申请公布日期 |
2013.07.25 |
申请号 |
US201213669324 |
申请日期 |
2012.11.05 |
申请人 |
DEPAOLI ALEXANDER M.;ORAL ELIF ARIOGIU;TAYLOR SIMEON I.;GARG ABHIMANYU |
发明人 |
DEPAOLI ALEXANDER M.;ORAL ELIF ARIOGIU;TAYLOR SIMEON I.;GARG ABHIMANYU |
分类号 |
A61K38/22;G01N33/53;A61K38/55;A61K45/00;A61P3/04;A61P3/10;A61P43/00;G01N33/68;G01N33/74 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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