发明名称 MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF
摘要 The present invention relates to a N-substituted matrinic acid derivative or matrine derivative, and its preparation method and uses. Specifically, the present invention relates to a compound of Formula (I) or (II) (wherein all the definitions of substituted groups are those mentioned in the specification), or a pharmaceutically acceptable salt, geometric isomer, stereoisomer, solvate, ester or prodrug thereof. The present invention further relates to a method for preparing the compound of the present invention, a pharmaceutical composition containing the compound, and uses thereof in manufacture of a medicament. The compound of the present invention can be used for prophylaxis and/or treatment of a disease or disorder associated with viral infection such as hepatitis B and/orhepatitis C and/or AIDS.
申请公布号 US2013190345(A1) 申请公布日期 2013.07.25
申请号 US201113812730 申请日期 2011.04.29
申请人 JIANG JIANDONG;SONG DANQING;DU NANA;PENG ZONGGEN;WANG YUPING;GAO LIMEI;HAN YANXING;LI XIN;LI CHUNXIN;CSPC ZONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAHUANG) CO., LTD.;INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES 发明人 JIANG JIANDONG;SONG DANQING;DU NANA;PENG ZONGGEN;WANG YUPING;GAO LIMEI;HAN YANXING;LI XIN;LI CHUNXIN
分类号 C07D471/16;C07D471/22 主分类号 C07D471/16
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