发明名称 Peptide vaccines for cancers expressing tumor-associated antigens
摘要 The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.
申请公布号 EP2465865(A3) 申请公布日期 2013.07.24
申请号 EP20120151719 申请日期 2008.02.21
申请人 ONCOTHERAPY SCIENCE, INC. 发明人 TSUNODA, TAKUYA;OHSAWA, RYUJI
分类号 C07K14/47;A61K39/00;A61P35/00;C07K14/00;C07K14/745;C12N5/10;G01N33/15;G01N33/50 主分类号 C07K14/47
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