The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.
申请公布号
EP2224004(B1)
申请公布日期
2013.07.24
申请号
EP20100163496
申请日期
2008.06.13
申请人
NOVARTIS AG
发明人
VAN HEEKE, GINO;HICKMAN, EMMA;DANAHAY, HENRY LUKE;TAN, PAMELA;GEICK, ANKE;VORNLOCHER, HANS-PETER