发明名称 |
USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS |
摘要 |
<p>Use of a compound of Formula 1 for inducing differentiation of mesenchymal stem cells to chondrocytes, and a pharmaceutical composition for treating a cartilage disease, which includes chondrocytes in which differentiation from mesenchymal stem cells is induced by the compound of Formula 1, are provided. Differentiation of the mesenchymal stem cells treated with the compound of Formula 1 to chondrocytes is specifically induced, and thus the compound can be used to effectively treat a cartilage disease such as arthritis, cartilage damage, and a cartilage defect.</p> |
申请公布号 |
EP2617415(A2) |
申请公布日期 |
2013.07.24 |
申请号 |
EP20110825472 |
申请日期 |
2011.09.16 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
HWANG, KI CHUL;JANG, YANG SOO;HAN, GYOON HEE |
分类号 |
A61K31/18;A61K31/47;A61P19/02;C12N5/077 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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