| 发明名称 |
HIV VACCINES BASED ON ENV OF MULTIPLE CLADES OF HIV |
| 摘要 |
<p>In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades fo Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.</p> |
| 申请公布号 |
CA2539068(C) |
申请公布日期 |
2013.07.23 |
| 申请号 |
CA20042539068 |
申请日期 |
2004.09.15 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
NABEL, GARY J.;CHAKRABARTI, BIMAL;KONG, WING-PUI;HUANG, YUE;YANG, ZHI-YONG |
| 分类号 |
A61K39/12;A61K39/21;C07K14/16 |
主分类号 |
A61K39/12 |
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