发明名称 Combination of IAP inhibitors and FLT3 inhibitors
摘要 The present invention relates to methods of treating hematological malignancies, including acute myeloid leukemia (AML), comprising the combination of a compound that inhibits the binding of the Smac protein to IAPs ("IAP inhibitor") and one or more pharmaceutically active agents; pharmaceutical compositions comprising said combination; and a commercial package comprising said combination. The present invention also relates to the use of IAP inhibitors in combination with one or more pharmaceutically active agents for the preparation of a medicament to treat hematological malignancies, including AML.
申请公布号 US8492429(B2) 申请公布日期 2013.07.23
申请号 US20070516062 申请日期 2007.11.27
申请人 GRIFFIN JAMES DOUGLAS;ZAWEL LEIGH;NOVARTIS AG 发明人 GRIFFIN JAMES DOUGLAS;ZAWEL LEIGH
分类号 A61K31/40;A01N43/38 主分类号 A61K31/40
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