| 发明名称 |
Expression of toxic genes in vivo in a non-natural host |
| 摘要 |
Compositions and methods are provided for expression of a toxic protein in a host cell preferably a bacterial host cell where at least one T7 RNA polymerase gene Is contained on the host cell chromosome and one or more genes encoding a T7 RNA polymerase inhibitor is located on an F' plasmid or on the chromosome.
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| 申请公布号 |
US8492117(B2) |
申请公布日期 |
2013.07.23 |
| 申请号 |
US20070517580 |
申请日期 |
2007.12.03 |
| 申请人 |
SAMUELSON JAMES C.;DAVIS THEODORE B.;RALEIGH ELISABETH A.;SOUTHWORTH MAURICE W.;NEW ENGLAND BIOLABS, INC. |
发明人 |
SAMUELSON JAMES C.;DAVIS THEODORE B.;RALEIGH ELISABETH A.;SOUTHWORTH MAURICE W. |
| 分类号 |
C12P21/02 |
主分类号 |
C12P21/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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