发明名称 |
Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases |
摘要 |
A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step wherein the eluting solution is a organic solution having a water content <3%. The solution contains at least: an organic solvent suitable for the subsequent radiolabelling reaction; a first compound (A) which is a molecule containing at least one acidic hydrogen and a second compound (B) which is an organic base sufficiently strong to be able to tear off the acidic hydrogen of the first compound (A) in an acid-base reaction leading to the formation of an organic salt (S).
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申请公布号 |
US8491790(B2) |
申请公布日期 |
2013.07.23 |
申请号 |
US20080664615 |
申请日期 |
2008.07.01 |
申请人 |
LEMAIRE CHRISTIAN;VOCCIA SAMUEL;AERTS JOEL;LUXEN ANDRE;MORELLE JEAN-LUC;PHILIPART GAUTHIER;TRASIS S.A.;UNIVERSITE DE LIEGE |
发明人 |
LEMAIRE CHRISTIAN;VOCCIA SAMUEL;AERTS JOEL;LUXEN ANDRE;MORELLE JEAN-LUC;PHILIPART GAUTHIER |
分类号 |
B01D15/08 |
主分类号 |
B01D15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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