发明名称 |
Methods for detection and quantification of analytes in complex mixtures |
摘要 |
The invention provides a method of detecting a nucleic acid analyte. The method consists of (a) contacting a mixture of nucleic acid analytes under conditions sufficient for hybridization with a plurality of target specific nucleic acid probes each having a different specifier; (b) contacting the mixture under conditions sufficient for hybridization with a corresponding plurality of antigenedigits each having a unique label, the plurality of anti-genedigits having a diversity sufficient to uniquely hybridize to genedigits within the specifiers, and (c) uniquely detecting a hybridized complex between one or more analytes in the mixture, a target specific probe, and an anti-genedigit.
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申请公布号 |
US8492094(B2) |
申请公布日期 |
2013.07.23 |
申请号 |
US201113027493 |
申请日期 |
2011.02.15 |
申请人 |
DIMITROV KRASSEN;DUNAWAY DWAYNE L.;THE INSTITUTE FOR SYSTEMS BIOLOGY |
发明人 |
DIMITROV KRASSEN;DUNAWAY DWAYNE L. |
分类号 |
C12Q1/68;G01N33/53;C07H21/04;C12N15/09;G01N21/78;G01N33/533;G01N33/566;G01N33/58 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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