发明名称 Method for inhibiting the growth of Mycobacterium tuberculosis by using CD13 receptor
摘要 The present invention discloses a method for inhibiting the growth of Mycobacterium tuberculosis, comprising: administering at least one selective binding agent such as an anti-CD13 antibody or a CD13 antagonist which can bind a CD13 receptor of a cell to inhibit infection of Mycobacterium tuberculosis. Administration of anti-CD13 antibody can reduce an expression level of the CD13 receptor, inhibit entry of Mycobacterium tuberculosis into monocytes, reduce survival of Mycobacterium tuberculosis in monocytes, and kill Mycobacterium tuberculosis effectively.
申请公布号 US8491894(B2) 申请公布日期 2013.07.23
申请号 US201113164137 申请日期 2011.06.20
申请人 LU YEN-TA;TSAI I-FANG;MACKAY MEMORIAL HOSPITAL 发明人 LU YEN-TA;TSAI I-FANG
分类号 A61K39/395;A61K39/00;A61K39/04 主分类号 A61K39/395
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