METHOD OF ASSESSING INFLUENCE OF HERPES VIRUS INFECTION ON ERYTHROCYTE MEMBRANE STABILITY IN NEWBORNS OF MOTHERS SUFFERED AGGRAVATED HERPES VIRUS INFECTION IN THIRD TRIMESTER OF PREGNANCY

摘要

FIELD: medicine.SUBSTANCE: newborn's peripheral blood is examined for malondialdehyde (MDA), and newborn's erythrocyte membrane ?-spectrin is determined by disk electrophoresis in polyacrylamide gel (10%) with sodium dodecyl sulphate; a discriminant function is calculated by formula as follows: Df=(-4.131×?-spectrin)+(+14.334×MDA); wherein Df is a discriminant function; ?-spectrin is erythrocyte stromal protein as a part of the erythrocyte membranes; MDA is a fatty acid peroxidation product in newborn's peripheral blood. If Df is more than (-0.235), a threatening instability of newborn's erythrocyte membranes is predicted that can lead to developing prenatal anaemia.EFFECT: higher accuracy of the prediction procedure.1 tbl