发明名称 |
Cyclosporine analogue molecules modified at amino acid 1 and 3 |
摘要 |
<p>Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula (I). The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.</p> |
申请公布号 |
AU2011342284(A1) |
申请公布日期 |
2013.07.18 |
申请号 |
AU20110342284 |
申请日期 |
2011.12.14 |
申请人 |
ISOTECHNIKA PHARMA INC. |
发明人 |
HEGMANS, ALEXANDER;FENSKE, BRUCE W.;TREPANIER, DAN J.;ABEL, MARK D.;SUGIYAMA, SHIN;URE, DAREN R. |
分类号 |
C07K7/64;A61K38/12;A61K38/13;C07K1/113 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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