| 发明名称 |
NON-FUCOSYLATED ANTIBODIES |
| 摘要 |
The present invention provides non-fucosylated therapeutic antibodies. More particularly, the invention provides non-fucosylated anti-CD20, anti-CD23 and anti-CD80 antibodies, which show enhanced antibody effector functions. Also provided are cells expressing the non-fucosylated antibodies and therapeutic methods using the non-fucosylated antibodies.
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| 申请公布号 |
US2013183288(A1) |
申请公布日期 |
2013.07.18 |
| 申请号 |
US20080593282 |
申请日期 |
2008.03.28 |
| 申请人 |
REFF MITCHELL;HARIHARAN KANDASAMY;ANN MACLAREN;WILLIAM SISK;BIOGEN IDEC INC. |
发明人 |
REFF MITCHELL;HARIHARAN KANDASAMY;ANN MACLAREN;WILLIAM SISK |
| 分类号 |
C07K16/28;A61K39/395;A61K45/06 |
主分类号 |
C07K16/28 |
| 代理机构 |
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