| 摘要 |
PROBLEM TO BE SOLVED: To provide an antibody specifically binding to an bioactive GIP.SOLUTION: There are provided particularly antibodies or the like comprising a heavy chain CDR1 including a specific amino acid sequence, a heavy chain CDR2 including a specific amino acid sequence, a heavy chain CDR3 including a specific amino acid sequence and/or a light chain CDR1 including a specific amino acid sequence, a light chain CDR 2 including a specific amino acid sequence, and a light chain CDR3 including a specific amino acid sequence. The antibody can specifically bind to the bioactive GIP, consequently, can be used for measurement of therapeutic effects of diabetes, abnormal insulin secretion, obesity, and calcium store, promoting effect of insulin secretion, or DPP4 inhibitory effects. |
