发明名称 |
Antagonist anti-CD40 antibody pharmaceutical compositions |
摘要 |
<p>Stable liquid pharmaceutical compositions comprising an antagonist anti- CD40 antibody as a therapeutically or prophylactically active component and methods useful in their preparation are provided. These compositions comprise the antagonist anti-CD40 antibody, a buffering agent to maintain the pH of the composition between about pH 5.0 and about pH 7.0, and an amount of arginine-HCl sufficient to render the liquid composition near isotonic. The stable liquid antagonist anti-CD40 antibody -containing pharmaceutical compositions of the invention find use in methods for treating proliferative diseases and diseases having an autoimmune and/or inflammatory component.</p> |
申请公布号 |
AU2007240507(B2) |
申请公布日期 |
2013.07.18 |
申请号 |
AU20070240507 |
申请日期 |
2007.04.17 |
申请人 |
NOVARTIS AG;XOMA TECHNOLOGY LTD. |
发明人 |
ARAYA, KIDISTI;CHEN, BAO-LU;OKHAMAFE, AUGUSTUS;LU, XIAOFENG |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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