发明名称 |
PROCESS FOR THE PRODUCTION OF HYALURONIC ACID IN ESCHERICHIA COLI OR BACILLUS MEGATERIUM |
摘要 |
A method of producing hyaluronic acid (HA) in Escherichia coli and Bacillus megaterium through episomal plasmid vectors wherein the gene is under the control of strong promoter T7, preferably under the control of strong promoter T7 of bacteriophage T7, and a system for the selection of stable bacterial strains producing high levels of hyaluronic acid, are provided. |
申请公布号 |
EP2614087(A1) |
申请公布日期 |
2013.07.17 |
申请号 |
EP20110764125 |
申请日期 |
2011.09.09 |
申请人 |
FIDIA FARMACEUTICI S.P.A. |
发明人 |
CORSA, VINCENZA;NEGRO, ALESSANDRO;BISICCHIA, SONIA |
分类号 |
C08B37/00;C12N9/10;C12N15/63;C12N15/75;C12P19/04;C12P19/26 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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