PHARMACEUTICAL AND FOOD COMPOSITION COMPRISING THE ANTIOXIDANT JUICE OF BORDEAUX RADISH RAPHANUS SATIVUS L. FOR PREVENTION OR CONTROL OF THROMBOSIS

摘要

PURPOSE: An ethyl acetate fraction of Raphanus sativus L. juice is provided to prevent acute oral toxicity and chronic toxicity with strong antioxidation activity and thermal stability, and to be processed in various forms such as a concentrate, a powder, a pill, and a tablet thereby being formulated for easy administration. CONSTITUTION: A method for manufacturing a Raphanus sativus L.-derived material which suppresses thrombin and platelet aggregation comprises the steps of: drying Raphanus sativus L. juice by reduced pressure at 60 deg. C or less; fractioning with organic solvents; and purifying by a molecular sieve. The material has thermal stability and acid stability at pH 2 and is a polymeric polysaccharide with a molecular weight of 30 kDa or greater. [Reference numerals] (AA) Thrombin time (seconds); (BB) Concentration (mg/ml)