| 发明名称 |
BENZIMIDAZOLE DERIVATIVES USED AS FXR AGONISTS |
| 摘要 |
The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.
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| 申请公布号 |
CA2697167(C) |
申请公布日期 |
2013.07.16 |
| 申请号 |
CA20082697167 |
申请日期 |
2008.08.19 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BENSON, GREGORY MARTIN;BLEICHER, KONRAD;GRETHER, UWE;MARTIN, RAINER E.;PLANCHER, JEAN-MARC;RICHTER, HANS;TAYLOR, SVEN;YANG, MINMIN |
| 分类号 |
C07D235/12;A61K31/4184;A61K31/4402;A61P1/16;A61P3/10;A61P9/00;A61P19/00;A61P25/16;A61P25/28;A61P35/00;C07D401/12;C07D405/12 |
主分类号 |
C07D235/12 |
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