发明名称 Pyrrazolopyridine compounds as dual NK1/NK3 receptor antagonists
摘要 The present invention relates to a compound of formula I wherein R1, R2, R3, Ar, and n are as defined herein or to a pharmaceutically active acid addition salt. Compounds of formula I show a high affinity simultaneously to both the NK1 and the NK3 receptors (dual NK1/NK3 receptor antagonists), useful in the treatment of schizophrenia.
申请公布号 US8487102(B2) 申请公布日期 2013.07.16
申请号 US201113083636 申请日期 2011.04.11
申请人 JABLONSKI PHILIPPE;NETTEKOVEN MATTHIAS;PATINY-ADAM ANGELIQUE;RATNI HASANE;STADLER HEINZ;HOFFMANN-LA ROCHE INC. 发明人 JABLONSKI PHILIPPE;NETTEKOVEN MATTHIAS;PATINY-ADAM ANGELIQUE;RATNI HASANE;STADLER HEINZ
分类号 C07D471/04 主分类号 C07D471/04
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