发明名称 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS
摘要 102041 The present disclosure includes methods and compositions for the treatment or prevention of diseases and disorders characterized by excessive or misregulated cellular proliferations, including methods for the treatment of tumors. The methods involve the use of pharmaceutical compositions comprising at least one agent selected from the group consisting of a LIF preparation, a BMP preparation, a BMPR signalling activator, and a LIFR signalling activator. The disclosure also includes LIF preparations, BMP preparations, BMPR signalling activator, and LIFR signalling activators, and methods for the identification of LIF preparations, BMP preparations, BMPR signalling activator, and LIFR signalling activators. The disclosure also includes pharmaceutical compositions comprising at least one agent selected from the group consisting of a LIF preparation, a BMP preparation, a BMPR signalling activator, and a LIFR signalling activator. mx : :In Q C!
申请公布号 AU2012202157(B2) 申请公布日期 2013.07.11
申请号 AU20120202157 申请日期 2012.04.13
申请人 STEMGEN S.P.A. 发明人 VESCOVI, ANGELO LUIGI;REYNOLDS, BRENT ALLAN
分类号 A61K38/18;A61P35/00 主分类号 A61K38/18
代理机构 代理人
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