发明名称 |
IMMUNIZATION AGAINST CLOSTRIDIUM DIFFICILE DISEASE |
摘要 |
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
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申请公布号 |
US2013177592(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
US201213457821 |
申请日期 |
2012.04.27 |
申请人 |
THOMAS, JR. WILLIAM D.;GIANNASCA PAUL J.;ZHANG ZHENXI;LEI WENDE;MONATH THOMAS P.;SANOFI PASTEUR BIOLOGICS, LLC |
发明人 |
THOMAS, JR. WILLIAM D.;GIANNASCA PAUL J.;ZHANG ZHENXI;LEI WENDE;MONATH THOMAS P. |
分类号 |
A61K39/08;A61K39/00;A61K39/02;C07K14/33;C07K16/12 |
主分类号 |
A61K39/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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